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Animals and Medicine

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Jack Howard Botting

Index

Texte intégral

Abel, J. J. 80

abolitionists 205

absorption 184

accursed fields 13

acetylcholine 169

actinomycin D. See cancer, anticancer, drugs

actively acquired tolerance 93

adenovirus
vaccine. See vaccination

adrenocorticotrophic hormone 156

Advertising Standards Authority 196

Afghanistan 10

agglutinins 133, 138

AIDS 53

Alderslade, R. 47

Algeria 21

alizarin dye 192

Allen, F. 148

allograft. See transplant

American civil war 32

American Physiological Society 145

American Society of Teratology 196

aminopterin. See cancer, anticancer, drugs

amylin 153

anaemia 84-85, 87, 130, 136, 206

anaesthesia 20, 161-166
anaesthetised
cat 169
dogs 82

anastomosis 88

angiocardiography 119

angiotensin

converting enzyme (ACE) 173
ACE inhibitors 173-174

receptor antagonists 174

animal
experimentation 61, 143, 163, 171, 177, 178. See also vivisection
research xiv, xviii, xix, xx, 14, 61, 85, 127, 181, 204
rights. See also antivivisection
literature 60, 104
movement xviii, 58
organisations xix-xx, 14, 54, 61, 143
propaganda xix, 24, 164, 177studies 24, 32, 80, 81, 90, 91, 181, 185

anthrax 11-15
vaccine. See vaccination

antibiotics 3, 36, 47, 52, 57, 58, 84, 178, 180, 206

antibiotic-induced colitis. See colon
penicillin. See penicillin

antibodies 24-26, 91, 96, 98, 100, 133, 134, 138, 206

anticoagulants 80-82, 82, 106, 119, 124-125, 134-136, 138, 139

anticoagulant therapy 119, 122, 124

antigens 134
antigenic cross reacting materials 74
transplantation 98
tumour 206-207

antilymphocyte serum (ALS) 97-98, 153

antineoplastic drugs 202

antiseptic powder 17

antiserum 25, 31, 69

antitoxin
equine 34, 68

Anti-Vaccination League.
See vaccination

antivivisection 47, 151-152. See also animal rights; vivisection
literature 37, 151-152
movement 69, 71, 168, 174, 178
organisations xvii-xix, 196
National Anti-Vivisection Society xvii, 172
propaganda 144

Arbois 20

Argentina 13

arteries. See blood, vessels

aspirin 157-158

asses 70

Association of American Physicians 148

Association of the British
Pharmaceutical Industry 193

atheromatous changes 115

Australia 188

Austria 7

autograft. See transplant

autonomic reflexes 171

Avery, G. xviii

azathioprine 96, 123

bacteriological diagnosis 70

Baginskys clinic 69

Bali 10

Bangladesh 18

Banting, F. 145

Bavaria 6

Bavarian Institution for Crippled Children 187

Bazy, L. 33

Beddow Bayly, M. 69

Belgium 7, 8

benzalkonium chloride 24

Berger, F. M. 185

Bergey, D. H. 34

Berlin 66, 69

Bernard, C. 170

Best, C. 145

beta blockers 172-173. See hypertension

bethanidine 171

biological assay 67, 151

bioprosthesis. See heart, valves, prosthesis

Birmingham 72

Björk-Shiley valve. See heart

Björk, V. 121. See also Björk-Shiley valve

Blakemore, C. xviii

blood xx, 4, 13, 14, 26, 35, 42, 60, 72, 80-86, 88, 89, 103-109, 115-118, 155, 162, 184, 185
bank 136, 137
bleeding disorder 124
cells 93, 133, 206
red 84, 97, 105, 136, 206
white 92, 95, 180
citrated 135-136
coagulation 121, 134
time 135
cold-blooded animals 127, 155
group 52, 60, 133, 134, 138
ABO 133-134
anti-Rh antibodies 138
haemoglobin
haemoglobinaemia 133
pressure 87, 88, 167-176. See also hypertension
sugar xx, 144-146, 146, 153
transfusion 127-140
reactions 134
services 137
vessels 88, 90, 100, 118, 123, 134, 144, 206
arteries 88, 103, 105, 128-129, 132-134, 155, 173. See also lungs, pulmonary artery
veins 31, 80, 88, 125, 128-129, 132-134. See also lungs, pulmonary vein

Blundell, J. ix, 131-133, 139

Boer War 32

bone marrow 206

Bordet, J. 41, 133
Bordetella pertussis 42

Borrel, A. 31

Boston Public Health Service Hospital 94

Bothrops jararaca 173

Boyle, R. 128

bradykinin 173
potentiating factor 173

Brazil 9

Breslau 145

Bretonneau, P. -F. 65

Brigham Hospital 90

Britain. See Great Britain

British Medical Journal 150

British Thoracic Society 53

bronchi 42
bronchitis 41, 46, 47

Bruschettini, A. 30

Burkitt, D. P. 205
Burkitt’s lymphoma 199

Burma 10

Burroughs Wellcome Research 96

Cabasso, V. J. 24

caged-ball valve. See heart

calcitonin 156

Calne, R. 96

calves. See cows

Cambridge University 150

cancer 130, 167, 199-209
anticancer
drugs 202, 203, 204
6-mercaptopurine 96
actinomycin D 203
aminopterin 203
vincristine 203
therapies 205-206
chemotherapy 58, 202-204, 205-206
carcinogenicity 194
metastases 206

Cannon, J. A. 93

captopril 37, 173

cardiac valves. See heart

cardioplegia. See heart

cardiopulmonary bypass. See heart

Carnot, P. 206

Carpentier, A. 124

Carrel, A. 88-89, 100, 139 cats 66, 88, 100, 104, 105, 159, 161, 171
rabid 20

cattle 13, 14, 19, 93, 117, 124, 143
twins 93

cauterization 24

Cawley, T. 144

celloidin 80

cellophane 80-82
tubing 81

Cesarean section 192

chemical messengers 155

Chemie Grünenthal 183

chemotherapy. See cancer, anticancer therapies

chickens 11, 12
cholera. See cholera

China 18

Chinese hamster 48

chloroform 164

chlorothiazide 171

cholera 54, 66
chicken 11-13, 21

chordae tendineae 117

Christie, G. 191

chronic
myelogenous leukaemia 201
renal failure. See kidney, renal failure toxicity 185, 194

Ciba Company 171

cisplatin 205

citrate 135

Clinical Society 70

Clostridium
difficile 180
perfringens 178
tetani 30

coagulation. See blood

Cobbett, L. 70

cold-blooded animals. See blood

Collip, J. 146

collodion 79

colloids 79

Colombia 18, 35

colon 180

colitis 87, 180-181
antibiotic-induced 180-181
enterocolitis 179

Colton, Q. 163

Columbia University 134

Committee on the Safety of Drugs 183, 194

Contergan 186

Cornelius, C. E. 156

Corrigan, D. J. 116

cortisone 97

Corynebacterium diphtheriae.

See diphtheria

cowpox 5

cows 14, 153, 156
calves 5, 121, 123

Crile, G. 133, 134, 139

Crimean war 32

crystalloids 79

cyclophosphamide 203

cyclosporin 97, 97-98, 98

cytotoxic drugs 204

Dacron felt 117

Dale, H. 150

Dameshek, W. 96

Darwin, E. 130

Davila, J. 121

Davis, L. E. 159

Davy, H. 161

decamethonium 169

deer 127

de la Condamine, C. -M. 4

Denis, J. -B. 129-130, 139

Denver 9

Department of Health 46

Descombey, P. 34

De Somer, P. 179

diabetes 79, 143-154
juvenile onset 143
late onset 152
mellitus 143, 153

dialysis 79-85, 87, 138
haemodialysis 79-80, 80-81
peritoneal 82-84

dicoumarol 125

diphtheria 65-74
antitoxin 66, 67, 68-70
bacillus diphtheriae 66
Corynebacterium diphtheriae 66
/tetanus/pertussis 43
toxin 66-70
vaccine. See vaccination

disc valves. See heart

Distaval 188

Distillers Company 184

dogs 21, 66, 80, 81, 82, 83, 88, 96, 98, 100, 104, 105, 109, 117, 123, 127, 128, 135, 143, 146, 153, 171
depancreatized 145
hounds 18
irradiated 95
rabid 20

Dollery, C. 167

Domagk, G. J. P. 177

Donnelly, E. J. 159

Dumas, J. B. A. 131, 139

Dunedin 170

Dunlop, D. 194

Duran, C. 123

Düsseldorf 186

earthworms 13

Edinburgh University 163

Elberfeld 177

elective cardiac arrest. See heart, open heart surgery

electrodialysis 124

embolism 104

Emmerez, P. 129

encephalopathy 45

Encyclopaedia Britannica 157

Enders, J. F. 61

endothelial cell 89

England 6, 7, 8, 17, 18, 41, 42, 43, 44, 62, 200, 201. See also Great Britain; United Kingdom

enterocolitis. See colon

epidemiology 205

epoprostenol 82

Epstein-Barr virus 199
vaccine. See vaccination

erythropoietin 84-85, 206

ether 161-164. See also anaesthesia

Ethiopia 9

ethyl alcohol 24

ethylene dibromide 163

Etris, S. 34

Europe 9, 19, 61, 73

Expert Committee on Drug Toxicity 194

Expert Committee on Rabies 25

extracorporeal circuit 80, 104-106. See also heart, open heart surgery

Fermi, E. 21

Ferreira, S. 173

ferrets 205

fetus
fetal abnormalities 158, 187-198

fever hospitals 65

Fiji vii, 44

Finland 21, 51

Fleming, A. 23, 177

flexible cusp valve. See heart

Florence, A. L. 186

Florey, H. 178

Flourens, M. J. P. 163

fluoroscopy 119

Folkman, J. 206

Food and Drugs Administration 183

Forschbach, J. 145

foxes 26
rabid 19

Fox, R. R. 192

France 8, 162

Franco-Prussian war 32

French Parliament 130

Frenkel, H. 186

fumagillin 206

ganglion 169

Ganter, G. 83

gardening 37

gastritis 87

geese 130

gene therapy 207

Germany 187

Gibbon, J. 104

Gilman, A. 202

Glenny, A. T. 70

glomerulonephritis 79, 87

glutaraldehyde 124

goats 5, 123

Gorer, P. A. 91, 98

grafts 90-99, 124

Graham, T. 79

Gram-positive microorganisms 179

granisetron 205. See also cancer

therapies

gravitator 132

Great Britain 18, 46, 69, 73, 162. See also England; United Kingdom; Wales

Greek, C. R. 196

Greek, J. S. 196

Greenwich Hospital 71

Grippex 186

Grist, G. 46

guanethidine 171

guinea pigs 12, 13-14, 24-25, 29, 31, 34, 66, 67, 70, 81, 83, 97, 124, 135, 138, 161, 177, 178-179, 180-181, 184, 189
germ-free 179
neonatal 181

Gunning, A. 123

Haas, G. 81

Habel, K. 25

Habig, W. 35

haemodialysis. See dialysis

haemoglobinaemia. See blood, haemoglobin

Haemophilus influenzae 51

haemorrhagic fever 53

Hamburg 188

Hamre, D. 178

hamsters 25, 178
kidney cells 25

hantaviruses 53

Harvey, W. 103, 127, 139, 155

Health Committee of the League of Nations 71

Hearse, D. 109

heart 87, 95, 103-104, 108, 118, 120, 127, 138, 155-156, 170
attack 149
cardioplegia
cardioplegic solution 107, 109-114
cold 112
coronary heart disease 174
failure 65, 108, 170, 173
congestive 107, 116, 173
heart-lung machine 107
open heart surgery 103-114
cardiopulmonary bypass 103-114
elective cardiac arrest 104, 108-109, 109
valves
allograft 123
artificial 115-126
Björk-Shiley valve 121
caged-ball valve 119-120
disc valve 120-122
flexible cusp valve 118
tilting disc valve 121
prosthesis 115-126
bioprosthesis 124-126
tricuspid 116
valvular disease 115-117
xenografts 123-124
ventricles 107, 115-117, 119
left ventricular hypertrophy 116
ventricular fibrillation 109
ventricular tachycardia 155

hens 12

heparin 81, 82, 104, 124, 138
heparinised blood 136

hepatitis B 207

vaccine. See vaccination

hexamethonium 170

Hib infection 52

Hickman, H. 162

Hippocrates 29

hirudin 80, 135

histamine sensitisation test 48

Hitchings, G. 96

Hodgkin’s disease 199, 200, 202

homograft. See transplant

Hopkins, B. E. 70

horses 5, 25, 31, 66, 67, 70, 98, 100
plasma 67

Hospital for Sick Children in Paris 68

Hughes, E. 148-149

human diploid cell line (HDC) 26

human diploid cell vaccine (HDCV) 26.
See vaccination

Hungary 21

Hustin, A. 135, 139

hydralazine 171

hydrophobia 18

hypertension 79, 90, 91
antihypertensive
drugs 170-176
ACE Inhibitors.
enzyme (ACE)
beta blockers. See beta blockers
therapy 169-170
malignant 167-176

hysteria 17

iatrogenic condition 180

immunisation 34, 43, 63, 71. See also vaccination
immune serum 24
immunological barrier 94

immunosuppressants 96, 100
drugs 96

impellor 132

India 10, 18, 34

influenza 35, 186
vaccine. See vaccination

inoculation 4, 71

insecticides 53

insulin xv, xx, 143-154, 156, 158

intense radiation 95

intubation 66

Iran 10, 18, 25, 26

Ireland 73

iron lungs 57

irradiation 95-96, 188

Jackson, C. 163

Japan 21

Java 10

Jenner, E. 5

Judaeus, I. 4

Jung, H. 184

Kansas 9

Kaufman, S. xiv

Kefauver-Harris Amendment 195

Keller, H. 183, 184, 193

Keller, K. A. 193

Kelsey, F. 187, 195, 196

Kendrick, F. J. 192

kidney 25, 79-85, 81, 87-100, 106, 144, 185, 200, 207

dialysis. See dialysis

polycystic disease 87

renal failure
acute 79
chronic (CRF) 79, 87
transplant. See transplant

Kiel 188

King, C. T. G. 192

Kitasato, S. 30, 31, 66, 70

Klebs, E. 66

Koch, R. 13

Kolff, W. 81

Koprowski, H. 25

Kosenow, W. 187

Krefeld 188

Kunz, K. 183, 184

Lacassagne, A. 204

lambs. See sheep

Lam, C. 123

Lancet, The 189

Landois, L. 133

Landsteiner, K. 52, 60, 133, 138, 139

Larrey, D. J. 32

laughing gas 163. See nitrous oxide

leeches 80, 134

Lenz, W. 184, 196

leukaemia 201-204
L1210 mouse leukaemia model 204

leukocytosis-promoting activity 48

Levine, P. 133, 138

Lewisohn, R. 135, 139

Lillie, F. 93

Little, C. 91, 98

lockjaw. See tetanus

Loeb, L. 93

Loeffler, F. 66

London 19, 45, 170, 173, 189

Long, A. 35

Longmire, W. P. 93

Lower, R. 128, 139

Ludlow 162

lungs
pulmonary
artery 104, 105, 115, 117
embolism 134

vein 115

Lyon 19

Macleod, J. 146

Madras 23

malaria 53
antimalarial drugs 53

malignant sore throat 65

Mary Imogene Bassett Hospital 95

Massachusetts General Hospital 105

Mayo Clinic 118
Foundation 90

McBride, W. G. 188

McLean, J. 81

McNeil, J. R. 158

measels
vaccine. See vaccination

Medawar, P. 91

Medical Advisory Committees 193

Medical Officers of Health 71

Medical Research Council 42

Medizinische Welt 186

Meister, J. 22

Melrose, D. G. 109

meningitis 51-53
Hib 51-52
vaccine. See vaccination
meningococcal
vaccine. See vaccination

meprobamate 185

metaperiodate oxidation 124

metastases. See cancer

Metchnikoff, É. 97

methotrexate 204

Metropolitan Life Insurance 143

Metropolitan Streets Act 19

mice 5, 14, 24-26, 29-31, 34, 42-43, 48, 53, 60-61, 81, 91, 93, 94, 95, 97, 98, 100, 153, 171, 172, 177-178, 183-185, 189, 192, 194, 203-204, 206
B16 melanotic melanoma 203
Lewis lung carcinoma 203
mouse protection test 42, 43, 177
non-obese diabetic [NOD] mouse 153
nude 153
P388 mouse leukaemia 203

microemboli 106

Miller, D. 47

Minkowski, O. 144, 145, 153

monkeys 33, 53, 59-61, 70, 83, 98, 100, 183, 185
aotus monkeys 53
red cells 138
rhesus monkeys. See rhesus factor

monoclonal antibodies 206

Moore, F. 98

Morocco 21

morphine 159

Morris, J. 46, 47

Morton, W. T. G. 163

Moscow 137

mosquito 53. See also malaria

Mückter, H. 183, 184

mules 5

mumps
vaccine. See vaccination

Murray, J. 81, 90

Mylar 118

mysid 127

National Anti-Vivisection Society.
See antivivisection, organisations

National Institute of Medical Research 151

neoplastic disease 199

Nepal 10

nephrectomy 85

Netherlands 6, 8

neurological illness 45

neuromuscular blocking drugs 36

newt 193

Nicolaier, Arthur 29

nitric oxide 174

nitrogen mustards 202-203. See also cancer

nitrous oxide 161

Nobel Prize 89, 92

North America 9, 57, 149. See also USA

North Dakota 125

ondansetron 205

open heart surgery. See heart

Owen, R. 93

ox 104

Oxford 178

Oxford University 92

ox serum ultrafiltrate 61

oxygenator 103

oxytocin 156

Pakistan 10, 18

pancreas 143-148, 150
cattle 143
dogs 144
extracts of 145
pancreatic islets 152
transplant. See transplant

papilloedema 167

papillomavirus 207
vaccine. See vaccination

paraesthesia 186

paralysis 20, 34, 58-61, 65, 87
infantile 58

parathyroid glands 156

Paris 130

paroxysmal cough 42

Pasteur Institute 23

Pasteur, Louis 3, 11-15, 20-24, 26, 66

Patarroyo, M. E. 53

Paton, W. 169-172

penicillin 36, 177-182, 193

Penicillium 177

Pepys, S. 128

pericarditis 87

peripheral neuritis 87, 186

peritoneal dialysis. See dialysis

peritonitis 84

pertussis 41-48
vaccine. See vaccination

Pfeiffer, R. F. J. 187

pharmacokinetic data 82

Philippines 18

Philips, F. 202

phocomelia 187

physicochemical methods 152

Physiology Department at Toronto 146

pigs 98, 104, 123, 138, 143, 153, 155-156
aortic valves 123. See also heart
transgenic 98

pituitary 156

plasmaphaeresis 26

platelet aggregation 82

Plegisol 112

Plymouth 19

pneumococci 53

pneumonia 41, 46, 58, 95, 96, 193
lobar pneumonia 58
pneumococcal
vaccine. See vaccination

poliomyelitis 57-63
poliovirus 60
vaccine. See vaccination

Pollock, T. 46, 47

polycystic kidney disease. See kidney

polymethylene-bisquaternary

ammonium salts 169

polyneuritis 186

post-exposure prophylaxis 22

post-partum haemorrhage 131

Pottevin, H. 23

Prichard, B. 172

pronethalol 172

prontosil 57, 178

propranolol 156, 172

prosthesis 103. See also heart, valves

protamine 106

prothrombin time 125

Provost, J. L. 131, 139

pseudomembrane 66, 180

puerperal sepsis 58

pyelonephritis 79, 87

rabbits 5, 12, 20, 25, 29, 30, 42, 53, 66, 68, 70, 80, 81, 82, 83, 85, 92, 95, 96, 98, 100, 104, 109, 124, 125, 134, 136, 153, 163, 170, 183, 206
pregnant 158, 191

rabies 17-26, 54
antigen 26
anti-rabies antibodies 25
immune globulin of human origin (RIGH) 26
vaccine. See also vaccination

raccoons 26

Ramon, G. 70

rats 82, 85, 104, 124, 155, 171, 173, 183, 185, 191
cotton rat 60
heart 109
pregnant 191
spontaneously hypertensive rats (SHR) 173
tissue 36

recombinant techniques 152

Reid, W. 163

rejection 24, 89-100, 123, 153. See also transplant
antirejection therapy 98

renal failure. See kidney, renal failure

Research Defence Society (RDS) xix, xx

reserpine 171

resorption 191

rhesus factor 138
rhesus monkeys 33
rhesus red cells 138

Richards, I. D. G. 158

Richardson, B. 79

Robertson, O. 136, 139

Robinson, K. 193

Rockefeller Institute 134

Rosa, M. 130

Ross, E. 47

Rous, P. 136, 139

Roux, E. 31, 66, 68, 69

Rowan, A. 152

Royal College of General Practitioners 47

Royal College of Surgeons 173

Royal Society 162

rubella
vaccine. See vaccination

Runner, M. 193

Russia 74

Sartwell, P. 35

Scandinavia 58

Scarpa, A. 130

Schardein, J. L. 193

Schering Company 145

Schick test 71

Schottstaedt, M. 167

Schumacher, H. 192

Schwartz, R. 96

scrub typhus
vaccine. See vaccination

″second set phenomenon″ 92

S (- )-enantiomers 192

septal defect 106

serotherapy 68

Sharpe, R. 11, 47, 157

sheep 13, 25, 123, 127
lambs ix, 129-130, 139
plasma 138

Sherrington, C. S. 33

Shiley, D. 121. See also Björk-Shiley valve

silage 125

Silastic ball 119

Simon, J. 7

Simpson, J. Y. 163

Singer, P. xviii

sipuleucel-T. See vaccination

skeletal malformations 187

Skipper, H. 204, 208

slow-release depot preparations 151

smallpox 3-14
vaccine. See vaccination

snakes 103, 155

Snell, G. D. 98

Sokolow, M. 167

Somalia 11

Somers, G. 190

SPf66. See vaccination

Sri Lanka 18

Staphylococcus aureus 177

Starling, E. H. 83

Starr, A. 119

stenosis 115

Stetson, R. 138

Stewart, G. 47

St Marys Hospital in London 192

Stop Huntingdon Animal Cruelty (SHAC) xviii

stroke xv, 174

St Thomas’s Hospital 109

Sudan 9

Sulawesi 10

sulphonamides 57, 178

surgery 31, 87-102, 161-162, 164, 169.
See also transplant
open heart. See heart

Sweden 5, 8, 58

sweet clover 125

sympathectomy 169

synaptobrevin 36

tacrolimus (FK 506) 98

tamoxifen 204

Tankersley, D. 35

Tanzania 53

Teflon 117

Temple, N. 205

Temple University 121

teratogenic effects 183

tetanus 5, 29-37, 41, 43, 46, 53
antiserum 31-32
anti-tetanus prophylaxis 33
antitoxin 30-34, 36
bacilli 5, 31
neonatal 35
toxin 30-31, 34, 36
vaccine. See vaccination

Thailand 18

thalidomide xv, 183-198

thrombocytopenia 82

thromboembolism 125

thyroid 144, 156

thyrotropin 156

tilting disc valve. See heart, valves

tissue typing 98

toad 155

Tolypocladium inflatum 97

toxin/antitoxin mixtures 70

toxoid 34-36, 37, 53, 70, 74

trachea 42
tracheotomy 69

transfusion. See blood

transplant 85, 87-102, 123. See also surgery
allograft 89, 91-92, 123
autograft 89, 91
cross grafting 94
homograft 89, 90
identical twin 94-95
islet cells 153
kidney 85, 87-102
xenografts 98, 123

tricuspid valve. See heart

tuberculosis 53, 193
vaccine. See vaccination

Tufts University 96

Turner, J. 136, 139

twin 93-96

typhoid 54

Tyzzer, E. E. 91, 98

United Hospitals of St Thomas and Guy 131

United Kingdom 183, 186, 194, 196. See also England; Great Britain; Wales

University of Minnesota 117

University of Toronto 143

USA 21, 46, 52, 61, 163, 187, 200. See also North America
base hospital 136
troops 35

vaccination 51-54, 207. See also immunisation
adenovirus 54
anthrax 13-15
Anti-Vaccination League 71, 72
diphtheria 54, 70-74
Epstein-Barr virus 199
hepatitis B virus 54, 207
Hib meningitis 54
human diploid cell (HDCv) 25
influenza 54
measels 54
meningococcal meningitis 54
mumps 54
papillomavirus 207
pertussis 41-48, 54
plague 54
pneumococcal pneumonia 54
poliomyelitis xv, 54, 59-63
PRP 52
rabies 21-26
rubella 54
scrub typhus 54
sipuleucel-T 207
smallpox 5-6, 7-9
SPf66 53
tetanus 34-37, 54
tubercolosis 53-54
typhoid 54
yellow fever 54

vaccinia virus 26

Vane, J. 173

vasopressin 156

veins. See blood

Vermont 58

vesicular eruption 4. See also smallpox

veterinary research 181

vincristine. See cancer, anticancer, drugs

virus fixe 21

vividiffusion 80

vivisection 196. See also antivivisection

voluntary muscle relaxants 169

von Behring, E. 31, 66, 67, 68, 70

von Mering, J. 144

Voss, R. 186

Wada, J. 121

Wakely, T. 164

Wales 7, 8, 41, 43, 44, 62, 200, 201. See also Great Britain; United Kingdom

Warfarin 124

Warkany, J. 189, 190, 196

Wegner, G. 82

Weicker, H. 188

Weidenbach, A. 187

Wells, H. 163

White, P. D. 117

whooping cough. See pertussis

Wiedeman, M. 188

Wilkins, R. 168

Williamson, C. 90

Williams, R. T. 192

wolves
rabid 19

Womens Hospital, Sydney 188

Woodruff, H. 97

World Health Assembly 9

World Health Organization (WHO) 9-12, 34, 36, 57, 63, 73

World War I 32, 35, 81, 89, 136

World War II 35, 42, 57, 91, 137, 202

Wren, C. 128, 139

xenografts. See transplant

xenotransplants. See xenograft

yellow fever
vaccine. See vaccination

Yersin, A. 66

Yugoslavia 21

Zaimis, E. 169-170

zinc endopeptidase enzyme 36

Zinsser, H. 7

Zülzer, G. 145

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