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Des sources du savoir aux médicaments du futur

 | 
Jacques Fleurentin
, 
Jean-Marie Pelt
, 
Guy Mazars

2. Études chimiques et pharmacologiques

Comparison of the antimicrobial activities of Syzygium jambos (L.) extracts with other tannin containing plant extracts

Corine Djadjo Djipa, Caroline Stévigny, M Delmée et Joëlle Quetin-Ledercq

Texte intégral

  • 1 Laboratory of Pharmacognosy, CHAM Unit, Université Catholique de Louvain, UCL 72.30 Av. E. Mounier (...)

1Note portant sur l'auteur1

  • 2 Laboratory of Pharmacognosy, CHAM Unit, Université Catholique de Louvain, UCL 72.30 Av. E. Mounier (...)

2Note portant sur l'auteur2

  • 3 Microbiology Unit, Université Catholique de Louvain, UCL 54.90 Av. Hippocrate, 54 1200 Brussels (B (...)

3Note portant sur l'auteur3

  • 4 Laboratory of Pharmacognosy, CHAM Unit, Université Catholique de Louvain, UCL 72.30 Av. E. Mounier (...)

4Note portant sur l'auteur4

Abstract

5Syzygium jambos (L.) Alston (Myrtaceae) is a widespread medicinal plant traditionally used in sub-Saharan Africa to treat infectious diseases. Acetone and aqueous extracts from the bark of Syzygium jambos were tested for antimicrobial activity in vitro by the agar dilution method in petri dishes. Both extracts showed some activity against the tested micro-organisms. They proved to be particularly effective on Staphylococcus aureus, Yersinia enterocolitica and coagulase negative staphylococci among which Staphylococcus hominis, Staphylococcus cohnii and Staphylococcus warneri. These properties seem to be related to the high tannin content of S. jambos extracts (respectively 77 and 83 % for the aqueous and acetone extracts determined according to the European Pharmacopoeia method) which were generally more active than Hamamelis virginiana, Krameria triandra, Alchemilla vulgaris and Rubus fruticosus extracts containing respectively 48, 44, 46 and 28 % tannins. Furthermore, elimination of tannins totally suppressed these antimicrobial activities.

6Djadjo Djipa C., Delmee M. and Quetin-Leclerq J. (2000) J. Ethnopharmacol, 71:307-313.

Notes de fin

1 Laboratory of Pharmacognosy, CHAM Unit, Université Catholique de Louvain, UCL 72.30 Av. E. Mounier, 72 1200 Brussels (Belgium) Email: mailto:leclercq@cham.ucl.ac.be.

2 Laboratory of Pharmacognosy, CHAM Unit, Université Catholique de Louvain, UCL 72.30 Av. E. Mounier, 72 1200 Brussels (Belgium) Email: mailto:leclercq@cham.ucl.ac.be.

3 Microbiology Unit, Université Catholique de Louvain, UCL 54.90 Av. Hippocrate, 54 1200 Brussels (Belgium)

4 Laboratory of Pharmacognosy, CHAM Unit, Université Catholique de Louvain, UCL 72.30 Av. E. Mounier, 72 1200 Brussels (Belgium) Email: mailto:leclercq@cham.ucl.ac.be.

© IRD Éditions, 2002

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